Archives: Events
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Structure-guided immunogen and immunotherapeutic design
Structural biology is essential for the rational design of novel vaccines, drugs, immunotherapeutics, or other biologics. Stabilised HIV-1 envelope antigens have facilitated the discovery of rare broad and potently neutralizing…
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Unwrapping insulin signalling by cryo-EM
The atomic structure of insulin has been known since the late 1960s, but it is only relatively recently that molecular detail has been obtained of the insulin receptor and of…
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The role of single-particle cryo-EM in discovering new drugs and vaccines
Single-particle cryo-EM, in being able to capture an entire spectrum of states of a biomolecular complex, is uniquely suited for drug discovery as well as development of vaccines. Increasingly the…
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Latest cryo-EM results from South Africa
The Electron Microscope Unit (EMU) at the University of Cape Town was established over sixty years ago as a regional imaging core facility serving the needs of the biological and…
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Effect of cyclonically draughted 35-60 kHz synthetic sounds of Odorrana tormota, Delphinapterus leucas, and male Anopheles gambiae on evoked Spatial Activity Index (SAI) and Protection Index (PI) in tropical mated female Anopheles gambiae
Malaria, a tropical disease caused by Plasmodium falciparum, is transmitted by the haematophagous mated female Anopheles gambiae. The P. falciparum is reported as the most prevalent malaria parasite responsible for…
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Investigation of the structure-function specialisation of Hsp70 chaperone machines of the main agent of malaria, Plasmodium falciparum
Malaria remains a major killer disease whose main victims are communities living in the sub-Saharan African region. Its main victims are children (<5 years) and pregnant mothers. One of the…
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SYNAPSE: a borderless scientific effort connecting global synchrotron resources to map animal brains
In response to the growing global demand for comprehensive connectome mapping, the SYNAPSE consortium was inaugurated in Singapore on January 15, 2020. It has since expanded beyond the Asia-Pacific region,…
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Cryogenic electron microscopy is revolutionizing biology: where are we now and the future ahead of us
Electron Microscopy under cryogenic temperatures is currently the fastest growing area in structural biology. Advances in instrumentation and software have made it possible for cryoEM to quite sustainably achieve resolutions…
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Application of Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) for quantitative analysis of biophysics research
Spectroscopic analysis technique has attained greater traction in Biophysics research and education for quantitative detection of bulk elemental composition of a wide variety of sample like powders, solids, liquids, suspensions…