Monoclonal antibodies neutralizing snake venom long & short chain three finger neurotoxins
Snakebite envenomation is a neglected tropical disease killing >135,000 people annually, predominantly in developing countries. Polyvalent antivenom is the only treatment, but it’s made through outdated technology. Monoclonal antibodies (mAbs) are the logical alternative for developing next-generation antivenom medicines. Here, we isolated a pair of antivenom mAbs that broadly cross-neutralized long and short chain three…