Visualizing antibody maturation for pathogenic viruses with cryo-EM
Discover how STEM-evolved monoclonal antibodies outpaced SARS-CoV-2 variants, revealed by cryo-EM structural insights.
Biophysics in Africa
Data Collection to Structure Refinement and Beyond
Tag: monoclonal antibodies
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Monoclonal antibodies neutralizing snake venom long & short chain three finger neurotoxins
Snakebite envenomation is a neglected tropical disease killing >135,000 people annually, predominantly in developing countries. Polyvalent antivenom is the only treatment, but it’s made through outdated technology. Monoclonal antibodies (mAbs) are the logical alternative for developing next-generation antivenom medicines. Here, we isolated a pair of antivenom mAbs that broadly cross-neutralized long and short chain three…