The kidney slit diaphragm looks like a fishnet
A comprehensive understanding of the molecular architecture of the slit diaphragm (SD), a critical component of the glomerular filtration barrier, is essential in elucidating renal filtration physiology and the mechanisms underlying kidney disease. Disruption of the SD is a hallmark of all forms of glomerulopathies, regardless of whether the cause is genetic, immunological, metabolic, or…