Dr Jason van Rooyen

Institutions

eBIC, Diamond Light Source

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About

Dr. Jason van Rooyen is the scientific lead of Diamond’s industry-dedicated “tube-to-structure” platform, eBIC for Industry. He completed his MSc and PhD studies in Structural Biology at the University of Cape Town and did his post-doctoral studies at the EMBL in Grenoble. He has spent several years in EM-focused scientific computing, deploying automated acquisition systems and HPC processing pipelines. Currently, he is helping pharma and bio-tech companies apply next-generation EM in their challenging research problems.

Selected recent publications
1.
Cannella, D. et al. miR-146a and miR-155 Delineate a MicroRNA Fingerprint Associated with Toxoplasma Persistence in the Host Brain. Cell Reports 6, 928–937 (2014). Cite
1.
Rooyen, J. M. van et al. Assembly of the Novel Five-Component Apicomplexan Multi-Aminoacyl-tRNA Synthetase Complex Is Driven by the Hybrid Scaffold Protein Tg-p43. PLOS ONE 9, e89487 (2014). Cite
1.
Khan, S. et al. Structural analysis of malaria-parasite lysyl-tRNA synthetase provides a platform for drug development. Acta Cryst D 69, 785–795 (2013). Cite
1.
van Rooyen, J., Abratt, V., Belrhali, H. & Sewell, T. Crystal structure of Type III glutamine synthetase: surprising reversal of the inter-ring interface. Structure 19, 471–483 (2011). Cite