About
Dr. Bridget Carragher is the founding Technical Director of the Chan Zuckerberg Imaging Institute since January 2023.
She received a PhD in Biophysics from the University of Chicago in 1987 and worked in a variety of positions, both in industry and academia before moving to the New York Structural Biology Center in 2015 to lead the Simons Electron Microscopy Center (SEMC), together with Clint Potter.
While at SEMC, Bridget and Clint directed the National Resource for Automated Molecular Microscopy (NRAMM), the National Center for CryoEM Access and Training (NCCAT), the National Center for In-situ Tomographic Ultramicroscopy (NCITU), and the Simons Machine Learning Center (SMLC). They also founded the company NanoImaging Services in 2007.
Selected publications
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Harrington, Kyle I., et al. Open-Source Tools for CryoET Particle Picking Machine Learning Competitions. bioRxiv, 5 Nov. 2024, https://doi.org/10.1101/2024.11.04.621608. Cite
Ermel, Utz, et al. “A Data Portal for Providing Standardized Annotations for Cryo-Electron Tomography.” Nature Methods, Oct. 2024, pp. 1–3, https://doi.org/10.1038/s41592-024-02477-2. Cite
Schwartz, Jonathan, et al. “Automating Workflows for Cryo-Electron Tomography with an Open-Source and Comprehensive Data-Pipeline.” Microscopy and Microanalysis, vol. 30, no. Supplement_1, July 2024, p. ozae044.346, https://doi.org/10.1093/mam/ozae044.346. Cite
Mendez, Joshua H., et al. “Automated Pipelines for Rapid Evaluation during CryoEM Data Acquisition.” Current Opinion in Structural Biology, vol. 83, Dec. 2023, p. 102729, https://doi.org/10.1016/j.sbi.2023.102729. Cite
Carragher, Bridget, and Clinton S. Potter. “Better, Faster, Cheaper, Smarter: Advancing Cryo-EM.” Microscopy and Microanalysis, vol. 29, no. Supplement_1, Aug. 2023, p. 1018, https://doi.org/10.1093/micmic/ozad067.514. Cite
Noble, Alex J., et al. “Reducing Effects of Particle Adsorption to the Air–Water Interface in Cryo-EM.” Nature Methods, vol. 15, no. 10, Oct. 2018, pp. 793–95, https://doi.org/10.1038/s41592-018-0139-3. Cite
Scapin, Giovanna, et al. “Structure of the Insulin Receptor–Insulin Complex by Single-Particle Cryo-EM Analysis.” Nature, vol. 556, no. 7699, Apr. 2018, pp. 122–25, https://doi.org/10.1038/nature26153. Cite
Lyumkis, Dmitry, et al. “Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer.” Science, vol. 342, no. 6165, Dec. 2013, pp. 1484–90, https://doi.org/10.1126/science.1245627. Cite
Suloway, Christian, et al. “Automated Molecular Microscopy: The New Leginon System.” Journal of Structural Biology, vol. 151, no. 1, July 2005, pp. 41–60, https://doi.org/10.1016/j.jsb.2005.03.010. Cite